Endocrine
CJC-1295 (No DAC)
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21+ · VERIFIED LAB USE
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Kisspeptin-10 is the C-terminal decapeptide fragment of kisspeptin-54, the product of the KISS1 gene, and is the minimum fragment that retains full activity at the KISS1R receptor (formerly GPR54).
Kisspeptin-10 is the C-terminal decapeptide fragment of kisspeptin-54, the product of the KISS1 gene, and is the minimum fragment that retains full activity at the KISS1R receptor (formerly GPR54).
The RF-amide C-terminus is the pharmacophore for this family, and the C-terminal amidation is essential - the free-acid form is substantially less active, so amide confirmation is part of the identity assay on every lot.
The sequence is relatively hydrophobic for its length and can be slow to dissolve in neutral water. A mildly acidic diluent shortens dissolution time considerably.
| Compound name | Kisspeptin-10 |
| Classification | Endocrine research compound |
| CAS number | 374675-21-5 |
| Molecular formula | C63H83N17O14 |
| Molecular weight | 1302.49 g/mol |
| Sequence | Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Purity (this lot) | 98.9% by RP-HPLC |
| Endotoxin | <0.5 EU/mg by LAL |
| Appearance | White lyophilized powder |
| Vial size | 10 mg |
| Solubility | Soluble in sterile water; mildly acidic diluent aids dissolution |
| Storage | Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days. |
| Released lot | PS-8975198 |
Vials arrive lyophilized and sealed under nitrogen. Bring the vial fully to room temperature before breaking the seal — opening a cold vial condenses atmospheric moisture onto the cake.
Direct diluent gently against the inside wall of the vial rather than onto the cake, and allow the material to dissolve without agitation. Vortexing shears longer sequences and introduces air.
Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days.
A full walkthrough is in the reconstitution guide, and the calculator will work out concentration and draw volume for this vial size.
Standard laboratory practice applies: appropriate personal protective equipment, no consumption, no administration to humans or animals, and disposal in accordance with institutional protocol and local regulation.
Both certificates below were generated against this specific lot and published before it was released to stock. Enter the lot number in the certificate lookup to retrieve them at any time. New to reading these? See how to read a certificate of analysis.
Kisspeptin-10 is the C-terminal ten residues of the 54-residue parent and retains full receptor activity.
The RF-amide terminus is the pharmacophore. The free-acid form is markedly less active, so amidation is confirmed on every lot.
Yes. The sequence is comparatively hydrophobic; a mildly acidic diluent speeds it up.
Kisspeptin-10 is supplied for in-vitro laboratory research only. It is not a drug, dietary supplement, food or cosmetic, is not approved by the FDA for any use in humans or animals, and no dosing guidance is published for it. Nothing on this page is a therapeutic, structure–function or health claim. Purchasers must be 21 or over and are responsible for compliance with all applicable law. Full terms of supply.
