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Home / Catalog / Neurobiology / DSIP
DSIP — sealed research vial, 10 mg
Lot PS-3123996 · 99.2% HPLC · 10 mg
Neurobiology research compound

DSIP

Delta Sleep-Inducing Peptide is a nonapeptide first isolated in 1977 from the cerebral venous blood of rabbits, and named for the electroencephalographic phenomenon observed in the experiments that identified it.

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About DSIP

Delta Sleep-Inducing Peptide is a nonapeptide first isolated in 1977 from the cerebral venous blood of rabbits, and named for the electroencephalographic phenomenon observed in the experiments that identified it.

The sequence is small, highly hydrophilic and carries no cysteine, which makes it one of the more straightforward peptides in the catalogue to handle - it dissolves quickly and requires no reducing precautions.

The N-terminal tryptophan makes it light-sensitive, so vials ship in opaque secondary packaging and solutions should be protected from direct light.

Specifications

Compound nameDSIP
ClassificationNeurobiology research compound
CAS number62568-57-4
Molecular formulaC35H48N10O15
Molecular weight848.81 g/mol
SequenceTrp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Purity (this lot)99.2% by RP-HPLC
Endotoxin<0.5 EU/mg by LAL
AppearanceWhite lyophilized powder
Vial size10 mg
SolubilityFreely soluble in water
StorageLyophilized: -20 C, desiccated, protected from light. Reconstituted: 2-8 C, use within 30 days.
Released lotPS-3123996

Handling & storage

Vials arrive lyophilized and sealed under nitrogen. Bring the vial fully to room temperature before breaking the seal — opening a cold vial condenses atmospheric moisture onto the cake.

Direct diluent gently against the inside wall of the vial rather than onto the cake, and allow the material to dissolve without agitation. Vortexing shears longer sequences and introduces air.

Lyophilized: -20 C, desiccated, protected from light. Reconstituted: 2-8 C, use within 30 days.

A full walkthrough is in the reconstitution guide, and the calculator will work out concentration and draw volume for this vial size.

Laboratory handling

Standard laboratory practice applies: appropriate personal protective equipment, no consumption, no administration to humans or animals, and disposal in accordance with institutional protocol and local regulation.

Documentation

Both certificates below were generated against this specific lot and published before it was released to stock. Enter the lot number in the certificate lookup to retrieve them at any time. New to reading these? See how to read a certificate of analysis.

PS-3123996-P
RP-HPLC purity report · DSIP 10 mg
99.2%
PS-3123996-E
LAL bacterial endotoxin assay · DSIP 10 mg
<0.5 EU/mg
PS-3123996-MS
Mass-spec identity confirmation · available on request
848.81

Frequently asked

Where does the name come from?

From the EEG phenomenon observed in the 1977 experiments in which it was first isolated.

Does it need special handling?

Only light protection, because of the N-terminal tryptophan. It is otherwise among the easier peptides in the catalogue to work with.

Does it contain cysteine?

No - no disulfide handling precautions are needed.

Terms of supply

DSIP is supplied for in-vitro laboratory research only. It is not a drug, dietary supplement, food or cosmetic, is not approved by the FDA for any use in humans or animals, and no dosing guidance is published for it. Nothing on this page is a therapeutic, structure–function or health claim. Purchasers must be 21 or over and are responsible for compliance with all applicable law. Full terms of supply.

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