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Home / Catalog / Endocrine / Ipamorelin
Ipamorelin — sealed research vial, 10 mg
Lot PS-2146000 · 99.4% HPLC · 10 mg
Endocrine research compound

Ipamorelin

Ipamorelin is a synthetic pentapeptide and a selective agonist at the growth hormone secretagogue receptor GHS-R1a, the same receptor targeted by ghrelin.

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About Ipamorelin

Ipamorelin is a synthetic pentapeptide and a selective agonist at the growth hormone secretagogue receptor GHS-R1a, the same receptor targeted by ghrelin.

It is notable in the literature for its receptor selectivity relative to earlier secretagogues such as GHRP-6 and hexarelin, which is why it appears so often in comparative receptor-binding work.

The sequence contains two non-standard residues - aminoisobutyric acid at position 1 and D-2-naphthylalanine at position 3 - which is what gives it stability against the proteases that degrade all-L-amino-acid sequences.

Specifications

Compound nameIpamorelin
ClassificationEndocrine research compound
CAS number170851-70-4
Molecular formulaC38H49N9O5
Molecular weight711.86 g/mol
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2
Purity (this lot)99.4% by RP-HPLC
Endotoxin<0.5 EU/mg by LAL
AppearanceWhite lyophilized powder
Vial size10 mg
SolubilityFreely soluble in water
StorageLyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days.
Released lotPS-2146000

Handling & storage

Vials arrive lyophilized and sealed under nitrogen. Bring the vial fully to room temperature before breaking the seal — opening a cold vial condenses atmospheric moisture onto the cake.

Direct diluent gently against the inside wall of the vial rather than onto the cake, and allow the material to dissolve without agitation. Vortexing shears longer sequences and introduces air.

Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days.

A full walkthrough is in the reconstitution guide, and the calculator will work out concentration and draw volume for this vial size.

Laboratory handling

Standard laboratory practice applies: appropriate personal protective equipment, no consumption, no administration to humans or animals, and disposal in accordance with institutional protocol and local regulation.

Documentation

Both certificates below were generated against this specific lot and published before it was released to stock. Enter the lot number in the certificate lookup to retrieve them at any time. New to reading these? See how to read a certificate of analysis.

PS-2146000-P
RP-HPLC purity report · Ipamorelin 10 mg
99.4%
PS-2146000-E
LAL bacterial endotoxin assay · Ipamorelin 10 mg
<0.5 EU/mg
PS-2146000-MS
Mass-spec identity confirmation · available on request
711.86

Frequently asked

What receptor does Ipamorelin target?

GHS-R1a, the growth hormone secretagogue receptor.

How does it differ from Hexarelin?

Both act at GHS-R1a, but Ipamorelin is reported in the literature as considerably more selective at that receptor.

What are Aib and D-2-Nal?

Non-standard amino acids - aminoisobutyric acid and D-2-naphthylalanine - included to resist enzymatic degradation.

Terms of supply

Ipamorelin is supplied for in-vitro laboratory research only. It is not a drug, dietary supplement, food or cosmetic, is not approved by the FDA for any use in humans or animals, and no dosing guidance is published for it. Nothing on this page is a therapeutic, structure–function or health claim. Purchasers must be 21 or over and are responsible for compliance with all applicable law. Full terms of supply.

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