Endocrine
CJC-1295 (No DAC)
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21+ · VERIFIED LAB USE
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CJC-1295 with DAC is the same 29-residue GRF analogue carrying an additional lysine at position 30 bearing a maleimidoproprionic acid Drug Affinity Complex.
CJC-1295 with DAC is the same 29-residue GRF analogue carrying an additional lysine at position 30 bearing a maleimidoproprionic acid Drug Affinity Complex.
That DAC moiety forms a covalent bond with cysteine-34 of serum albumin, which is the entire point of the variant and the reason it behaves so differently from the No DAC form in any assay involving serum.
The added moiety raises molecular weight to roughly 3647 g/mol against 3368 for the No DAC form - a difference worth accounting for when preparing molar solutions.
| Compound name | CJC-1295 (DAC) |
| Classification | Endocrine research compound |
| CAS number | 446262-90-4 |
| Molecular formula | C165H269N47O46 |
| Molecular weight | 3647.2 g/mol |
| Sequence | Modified GRF(1-29) with Drug Affinity Complex at Lys30 |
| Purity (this lot) | 99.0% by RP-HPLC |
| Endotoxin | <0.5 EU/mg by LAL |
| Appearance | White lyophilized powder |
| Vial size | 5 mg |
| Solubility | Soluble in sterile or bacteriostatic water |
| Storage | Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days. |
| Released lot | PS-9887787 |
Vials arrive lyophilized and sealed under nitrogen. Bring the vial fully to room temperature before breaking the seal — opening a cold vial condenses atmospheric moisture onto the cake.
Direct diluent gently against the inside wall of the vial rather than onto the cake, and allow the material to dissolve without agitation. Vortexing shears longer sequences and introduces air.
Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days.
A full walkthrough is in the reconstitution guide, and the calculator will work out concentration and draw volume for this vial size.
Standard laboratory practice applies: appropriate personal protective equipment, no consumption, no administration to humans or animals, and disposal in accordance with institutional protocol and local regulation.
Both certificates below were generated against this specific lot and published before it was released to stock. Enter the lot number in the certificate lookup to retrieve them at any time. New to reading these? See how to read a certificate of analysis.
Drug Affinity Complex - a maleimidoproprionic acid moiety that covalently binds albumin.
Protocols using the DAC form typically call for smaller masses, so the 5 mg vial is the standard format.
No. Albumin binding makes them functionally distinct reagents.
CJC-1295 (DAC) is supplied for in-vitro laboratory research only. It is not a drug, dietary supplement, food or cosmetic, is not approved by the FDA for any use in humans or animals, and no dosing guidance is published for it. Nothing on this page is a therapeutic, structure–function or health claim. Purchasers must be 21 or over and are responsible for compliance with all applicable law. Full terms of supply.
