Endocrine
CJC-1295 (DAC)
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21+ · VERIFIED LAB USE
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CJC-1295 without DAC - also catalogued as Modified GRF (1-29) - is a 29-residue analogue of growth-hormone-releasing hormone carrying four amino-acid substitutions that improve stability against enzymatic cleavage relative to native GRF.
CJC-1295 without DAC - also catalogued as Modified GRF (1-29) - is a 29-residue analogue of growth-hormone-releasing hormone carrying four amino-acid substitutions that improve stability against enzymatic cleavage relative to native GRF.
The distinguishing feature of this variant is the absence of the Drug Affinity Complex moiety. Without DAC the peptide does not covalently bind serum albumin, which is why bench protocols treat the two variants as separate reagents rather than interchangeable ones.
It is supplied as the acetate salt. The C-terminal amide should be noted when calculating molar concentrations from mass.
| Compound name | CJC-1295 (No DAC) |
| Classification | Endocrine research compound |
| CAS number | 863288-34-0 |
| Molecular formula | C152H252N44O42 |
| Molecular weight | 3367.9 g/mol |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Purity (this lot) | 99.8% by RP-HPLC |
| Endotoxin | <0.5 EU/mg by LAL |
| Appearance | White lyophilized powder |
| Vial size | 10 mg |
| Solubility | Soluble in sterile or bacteriostatic water |
| Storage | Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days. |
| Released lot | PS-0771773 |
Vials arrive lyophilized and sealed under nitrogen. Bring the vial fully to room temperature before breaking the seal — opening a cold vial condenses atmospheric moisture onto the cake.
Direct diluent gently against the inside wall of the vial rather than onto the cake, and allow the material to dissolve without agitation. Vortexing shears longer sequences and introduces air.
Lyophilized: -20 C, desiccated. Reconstituted: 2-8 C, use within 30 days.
A full walkthrough is in the reconstitution guide, and the calculator will work out concentration and draw volume for this vial size.
Standard laboratory practice applies: appropriate personal protective equipment, no consumption, no administration to humans or animals, and disposal in accordance with institutional protocol and local regulation.
Both certificates below were generated against this specific lot and published before it was released to stock. Enter the lot number in the certificate lookup to retrieve them at any time. New to reading these? See how to read a certificate of analysis.
The DAC variant carries a Drug Affinity Complex moiety that binds serum albumin. This one does not. They are distinct reagents and are not interchangeable in protocol.
Yes - the two names refer to the same 29-residue sequence with the same four substitutions.
The No DAC form, by a wide margin, though both are held in stock.
CJC-1295 (No DAC) is supplied for in-vitro laboratory research only. It is not a drug, dietary supplement, food or cosmetic, is not approved by the FDA for any use in humans or animals, and no dosing guidance is published for it. Nothing on this page is a therapeutic, structure–function or health claim. Purchasers must be 21 or over and are responsible for compliance with all applicable law. Full terms of supply.
